高级毒理学家（远程职位）
Senior Toxicologist (REMOTE ROLE)
高级毒理学家
为支持ICF的快速发展和不断扩大的客户基础，我们正在寻找一名高级毒理学家加入我们的健康科学组合。该团队由100多名科学专业人员组成，提供毒理学、危害评估、流行病学、风险评估、暴露评估、环境建模及相关支持，涵盖潜在有害物质的全谱，包括化学品和微生物。我们专长于识别和量化环境污染物（包括金属、农药、工业化学品和挥发性有机化合物）对人类健康和环境的影响。
高级毒理学家的项目工作将支持联邦机构（如美国环保署和国家环境卫生科学研究所）在设计、实施和报告危害研究及环境污染物的人类健康风险评估方面的工作。特别是，成功候选人将在识别、解释和整合分子生物学、机制毒理学和新方法（NAMs）数据方面提供领导力，以支持危害识别、作用模式分析、系统综述和人类健康风险评估。该职位将涉及评估多种证据来源，包括基因表达、-组学、细胞和分子检测、基于通路的数据以及不良结局路径（AOP）框架。
地点：远程办公
你将负责
- 同时参与多个涉及毒理学数据、系统文献综述和风险评估项目的项目管理和技术领导活动。协助定义项目范围和目标，并作为客户和内部项目团队的主要联系人。
- 撰写毒理学报告，包括撰写方法、结果和讨论部分，根据测试结果审查毒理学结论，并将发现综合成证据权重分析。
- 撰写方案和指导文件、毒理学报告、论文、项目描述和提案。
- 与多学科的毒理学家、生物学家、流行病学家和统计学家合作，解决复杂的科学和监管问题。
- 执行毒理学系统综述任务，包括文献筛选、研究质量评估、研究数据提取、剂量-反应分析、纳入NAMs和机制数据以及数据综合。
- 监督、指导和培训初级和中级员工。
基本资格
查看英文原文
SENIOR TOXICOLOGIST
To support ICF’s dynamic growth and expanding client base, we are seeking a Senior Toxicologist to work in our Health Science Portfolio. This group of 100+ science professionals provide toxicology, hazard assessment, epidemiology, risk assessment, exposure assessment, environmental modeling, and related support that addresses the full spectrum of potentially hazardous agents, including chemicals and microbes. We specialize in identifying and quantifying the effects of environmental pollutants—including metals, pesticides, industrial chemicals, and volatile organic compounds—on human health and the environment.
The Senior Toxicologist’s project work would support federal agencies (such as U.S. EPA and NIEHS) in the design, conduct, and reporting of hazard studies and human health risk assessments for environmental pollutants. In particular, the successful candidate will provide leadership in the identification, interpretation, and integration of molecular biology, mechanistic toxicology, and new approach methodologies (NAMs) data to support hazard identification, mode-of-action analyses, systematic review, and human health risk assessments. The role will involve evaluating diverse evidence streams including gene expression, -omics, cellular and molecular assays, pathway-based data, and adverse outcome pathway (AOP) frameworks.
Location: Remote
What you’ll do
- Project management and technical leadership activities on multiple projects concurrently involving toxicology data, systematic literature reviews, and risk assessment. Assist in the definition of project scope and objectives and serve as the primary point of contact for client and internal project teams.
- Toxicological report development, including writing methods, results, and discussion sections, reviewing toxicological conclusions based on the test results, and synthesizing findings into a weight of evidence analysis.
- Draft protocol and guidance documents, toxicological reports, manuscripts, project descriptions, and proposals.
- Collaborate with multidisciplinary teams of toxicologists, biologists, epidemiologists, and statisticians to address complex scientific and regulatory questions.
- Toxicology systematic review tasks including literature screening, study quality evaluation, study data extraction, dose-response analysis, incorporation of NAMs and mechanistic data, and data synthesis.
- Supervise, mentor, and train junior- and mid-level staff.
Basic Qualifications:
- Ph.D. in toxicology, pharmacology, environmental science, or related subject with 5+ years of experience in academic, industry, regulatory, or consulting fields.
- OR Master’s degree in toxicology, pharmacology, environmental science, or related subject with 10+ years of experience.
Preferred Qualifications:
- Strong working knowledge of mechanistic toxicology and molecular biology
- Experience integrating mechanistic, animal, and human evidence into a weight-of-evidence evaluation
- Experience with mode of action and adverse outcome pathway (MOA and AOP) concepts, frameworks, and analyses
- Experience evaluating molecular, cellular, and mechanistic data including transcriptomics, proteomics, metabolomics, and high-throughput screening assays
- Experience with endocrine disruptors, PFAS, PAHs, and other emerging contaminants
- Experience in cancer assessment
- Experience with NAMs, molecular biology techniques, and mechanistic data for regulatory decision-making
- Experience with systematic literature review
- Strong quantitative skills with experience in dose-response analysis, benchmark dose modeling, pathway enrichment analyses, or similar modeling experience
- Strong written and oral communication skills
- Proactive and problem-solving approach to challenges
- Experience/familiarity with government programs
- Excellent organizational skills and attention to detail
- Ability to prioritize, multi-task, and work under strict deadlines in a fast-paced environment
- Experience with project management and staff leadership
- Demonstrated ability to formulate and execute technical approaches to solving scientific questions
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Bot and Third-Party Applications
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Working at ICF
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At ICF, we are committed to ensuring a fair interview process for all candidates based on their own skills and knowledge. As part of this commitment, the use of artificial intelligence (AI) tools to generate orassistwith responses during interviews (whether in-person or virtual) is notpermitted. This policy is in place tomaintainthe integrity and authenticity of the interview process.
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Pay Range - There are multiple factors that are considered in determining final pay for a position, including, but not limited to, relevant work experience, skills, certifications and competencies that align to the specified role, geographic location, education and certifications as well as contract provisions regarding labor categories that are specific to the position.
The pay range for this position based on full-time employment is:
$81,499.00 - $138,549.00Nationwide Remote Office (US99)Originally posted on Himalayas